What is the role of radiotherapy for management of soft tissue and bone sarconas?

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DOI:  https://www.doi.org/10.31917/2204267

Radiation therapy is a treatment approach in soft tissue and bone sarcomas, and it is usually used in a combination with surgical treatment. High local control is a problem that remains relevant, as well as reducing the treatment toxicity. Modern technologies such as intensity-modulated radiation therapy, stereotactic radiation therapy, and hadron therapy have expanded the use of radiation therapy in the treatment primary and metastatic sarcomas. The effectiveness of radiation therapy can be enhanced in combination with chemotherapy and targeted therapy. The future is in a personalized approach based on the assessment not only the tumor parameters and the patient condition but also individual radiosensitivity. This review defines the role of radiation therapy soft tissue and bone sarcomas.