Infrared spectroscopy in detection of brain tumor of different morphological structure

The study considers the results of application of blood serum infrared spectroscopy as a diagnosis method of brain tumors
with various morphological structure. The study involves 99 patients with brain tumors (glioblastomas were diagnosed
in 22 patients, astrocytomas – in 21, neuromas – in 13, meningiomas – in 12, ependymomas – in 11, oligodendroastrocytomas
– in 10, hypophyseal adenomas – in 10 patients), 16 patients with acute cerebrovascular accidents of ischemic
type, 24 patients with severe traumatic brain injury and 20 healthy volunteers. In each studied case, 13 ratios of peak
heights of blood serum infrared spectrum absorption bands were studied applying infrared spectroscopy (IRS). The results
of morphological and immunohistochemical examinations were compared with the results of blood serum IRS data of
patients with brain tumors. There were statistically significant correlations between the histological nature of brain tumors
and IRS values. Statistically significant differences between the blood serum IRS of patients with tumor, non-tumor brain
lesions and healthy volunteers were also found.