The journal «Practical oncology» / Т.19, №3, 2018, Critical view on the development of oncology in the last 20 years

20 YEARS OF TARGETING THERAPY OF SOLID TUMORS. SUCCESSES AND FAILURES

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DOI: https://www.doi.org/10.31917/1903183
Abstract:

This article critically reviews twenty years’ experience of targeted therapy use for the treatment of solid tumors. Resistance mechanisms, predictive biomarkers and inter-tumor differences in targeted therapy efficacy are discussed. Data for pros and cons of the use of modern multigene panels in routine practice to personify therapy are critically
reviewed.

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