Advances in fundamental oncology: Year 2019 update



This paper describes the most remarkable advances in fundamental and translational oncology occurred within the year 2019. The discussion includes various aspects of acquired tumor drug resistance, breakthrough in the treatment of RAS-mutated tumors, use of CRISPR-Cas9 technology for genome editing, results of genome profiling-driven clinical trials, progress in the metastasis research etc. The article is aimed at clinical oncologists, various professionals working in medicine and biology, students etc.