Alkalization therapy in cancer treatment

Tumor acidosis is a key characteristic that contributes to cancer progression, arising from metabolic changes, hypoxia, and the properties of the tumor microenvironment. Alkalinizing therapy aims to neutralize the acidic tumor microenvironment using alkalizing agents such as sodium bicarbonate. Research indicates that alkalinizing therapy can enhance the efficacy of standard treatments like chemotherapy and improve overall patient survival. However, despite promising results, skepticism within the scientific community persists due to a lack of reliable data and low commercial appeal of such methods. This paper analyzes existing clinical data on the application of alkalinizing therapy in oncology and discusses potential mechanisms of action for this treatment approach.