The role of androgen receptor in breast cancer. Reviewwork



An important feature of breast cancer is its biological heterogeneity. Often this causes difficulties in choosing a systemic therapy option (chemotherapy, endocrine, targeted therapy) in a particular patient. Knowledge of molecular biological markers in a tumor allows not only to characterize its sensitivity to drug treatment, but also to more clearly determine the potential for invasion and metastasis. The search for and introduction into practice new molecular markers makes it possible to individualize treatment. Determination of androgen receptors expression in tumor tissue can become an additional prognostic factor and can be used in therapy planning, including such an aggressive subtype as triple negative breast cancer