The role of radiation therapy in management of pancreatic cancer

Radiation therapy is a critical component of the treatment of cancer, but its role in the treatment of pancreatic cancer is ambiguous. Early metastasis, radioresistance of pancreatic adenocarcinoma, proximity to organs with low tolerance to ionizing radiation limit the possibilities of conventional radiation therapy and explain the advantage of chemotherapy in a number of studies. At the same time, the high risk of local progression stimulates the search for more effective local treatment. New prospects are associated with high-precision radiotherapy technologies, especially stereotactic radiation therapy with an 
ablative dose level to overcome the radioresistance of various cancers, including pancreatic cancer