The journal «Practical oncology» / Т.18, №1 - 2017, The most important achievements in oncology in 2016

Repurposing drugs in oncology



Drug repurposing (repositioning) is the process of developing new indications for existing drugs. The aim of repurposing drugs in oncology is applying existing,
well-characterized and well-used non-cancer drugs as agents in anticancer treatment. The present review summarized recent information about the anti-cancer effects and mechanisms of anti-cancer action for several drugs, commonly used for other medical indications (nitroglycerin, diclofenac, metformin, cimetidine, mebendazole).